Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp101 | Adrenal and Neuroendocrine - Basic | ECE2019

Infiltrating CD68+/CD163+ macrophages regulate Gonadotroph-tumour invasion through collagen remodelling

Principe Moitza , Chanal Marie , Ilie Mirela D. , Vasiljevic Alexandre , Jouanneau Emmanuel , Hennino Ana , Raverot Gerald , Bertolino Philippe

Introduction: Pituitary Neuroendocrine tumours (PitNETs) present heterogenic characteristics based on their hormonal expression and secretion. While most PitNETs have a slow progression rate, a subset of them exhibit an aggressive behaviour with recurrence properties despite current surgery, radio- and chemotherapy. To explore new clinical strategies based on immunotherapy we initiated a systemic cartography of the pituitary tumour immune microenvironment (PiTME).<p class=...